Best EHR for MAT Programs in 2026
Best EHR platforms for medication-assisted treatment (MAT) programs, evaluated on EPCS workflows, compliance controls, SUD documentation depth, and revenue-cycle reliability.
Our Top Picks at a Glance
Ease
AI-native BH platform with EPCS support, integrated operations tooling, and strong clinician-productivity workflows.
AZZLY Rize
Purpose-built SUD platform with ASAM-oriented workflows, compliance controls, and integrated RCM.
Valant
Strong psychiatry-first prescribing experience with EPCS and medication-management depth.
Netsmart (myAvatar)
Enterprise behavioral-health platform for large organizations with complex reporting and multi-site operations.
PIMSY
Balanced clinical and business tooling for mid-size organizations blending MAT with broader behavioral health services.
What MAT Programs Need from an EHR
MAT programs run at the intersection of prescribing, behavioral health documentation, compliance, and payer operations. You need an EHR that supports controlled-substance prescribing workflows, maintains clean clinical documentation, and reduces administrative friction in authorization and billing.
Selection Criteria
- EPCS and prescribing workflow quality: controlled-substance workflows should be reliable and efficient for high-volume medication management.
- SUD documentation depth: ASAM-aligned assessments and structured treatment documentation reduce payer friction.
- Compliance posture: organizations should validate 42 CFR Part 2-oriented controls, auditability, and consent handling behavior.
- Authorization and billing operations: prior auth visibility, denial prevention, and clean-claim workflows are central to MAT economics.
- Program-level reporting: leadership needs operational dashboards that connect clinical throughput to financial outcomes.
Where Ease Fits Best
Ease is a strong choice for MAT organizations that want an AI-native operating model. Its workflow automation, Voice AI capabilities, and integrated operational reporting can materially reduce clinician documentation burden while improving admissions, authorization, and billing visibility.
Bottom Line
Prescriber-heavy MAT practices may prioritize prescribing ergonomics first, while multi-program organizations often need deeper end-to-end operations support. For organizations optimizing both clinician productivity and business performance, Ease belongs in the top tier of MAT evaluations.